Treatment of skin diseases by means of personalised medicine (genodermatoses)
Prof. Stingl is a specialist dermatologist and venerologist in Vienna. Here, he is the Head of the Clinical Department of Immunodermatology and Infectious Skin Diseases at the Medical University of Vienna. Together with the care of patients and teaching medical students, the focal points of the activity of Prof. Stingl’s department in Vienna also include research into various conditions and the development of new therapeutic options. Here, in particular, the focus is on immunodermatology, allergology and the treatment of infectious skin diseases and sexually transmitted diseases such as HIV.
Of course, as a specialist dermatologist and venereologist, Prof. Stingl utilises the traditional clinical methods of treatment and research emphases; however, he is also concerned with the increased advancements in the field of translational medicine. This is considered to include the step from preclinical research to clinical development and the translation of an animal model into the application for the patient.
Particularly in the rapid development of so-called personalised and molecular medicine, there arises for Prof. Stingl the imperative of treating patients with up to date and internationally state of the art techniques. Accordingly, the students in the Clinical Department of Immunodermatology and Infectious Skin Diseases at the Medical University of Vienna are also trained in accordance with the most up to date level of medical knowledge. Hence, in Prof. Stingl’s department, there also comes about an attractive sphere of activity in the field of research for degree theses and dissertations.
Prof. Stingl himself studied medicine at the University of Vienna, where he read for his doctorate and completed his specialist dermatovenerological training before working on fundamental issues in the field of the immunobiology and immunopathology of the skin as a research fellow at the National Institutes of Health, Bethesda, Maryland, U.S.A. He pursued this successfully on his return to Austria, first in Innsbruck, then in Vienna. After obtaining his licence to teach in 1980 and his appointment as Associate Professor in 1985, he was appointed Professor of Dermatology and Venereology in 1992 and, in association with this, Head of the Clinical Department of Immunodermatology and Infectious Skin Diseases at the University Dermatology Hospital of the Medical University of Vienna.
The areas of research of the specialist dermatologist and venereologist in Vienna include, in particular, the immunological functions of the skin as an organ. So, Prof. Georg Stingl discovered the immunological function of the epidermal Langerhans cells. He was also able to prove that the epidermal Langerhans cells represent a target structure for an HIV infection via the skin.
The specialist dermatologist and venereologist is also a member of important specialist scientific advisory bodies, a consultant for the most renowned biomedical journals and an honorary member of the most prestigious professional associations such as the Society of Investigative Dermatology and the European Society for Dermatological Research. He is an active member of the Austrian Academy of Sciences, a Member of the Board of the German “Leopoldina” National Academy of Sciences and has recently been elected to the Institute of Medicine of the US National Academies.
Direct immunofluorescence as evidence of tissue-bound immunoglobulins and complement components
Indirect immunofluorescence and ELISA technique as evidence of circulating autoantibodies
Evidence of leukocyte subpopulations in peripheral blood and in tissue samples
Evidence of cytokines in the serum
Atopy patch test
PRICK and intracutaneous test
Autologous Serum Skin Test (ASST)
Exposure to medications with in-patient monitoring
III. Infectious skin diseases – sexually transmitted diseases
Native diagnostics: methylene blue and Gram staining of N. gonorrhoeae, dark field and optical fluorescent evidence of T. pallidum, Tzanck smear as evidence of viruses, KOH as evidence of yeasts and filamentous fungi, evidence of mites