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Treatment · Esophageal Surgery

Reflux Surgery (Fundoplication): Surgical Treatment of Reflux Disease and Heartburn

Brief overview — the essentials first

Reflux surgery (fundoplication) is a minimally invasive procedure in which the upper part of the stomach is wrapped around the lower end of the esophagus to strengthen the sphincterand prevent the reflux of stomach acid. It is performed when conservative or medical treatment does not provide sufficient relief from heartburn and acid reflux. In specialized clinics for visceral surgery, the procedure is usually performed laparoscopically, which allows for a particularly minimally invasive approach with small incisions and rapid healing. The Nissen fundoplication and the Toupet fundoplication are the most common procedures and result in long-term relief of symptoms for most patients.

Reflux surgery—also known as reflux operation or fundoplication—is a surgical procedure used to treat chronic heartburn and gastroesophageal reflux disease when medication no longer provides sufficient relief.
During the procedure, the upper part of the stomach is wrapped around the lower end of the esophagus to strengthen the sphincter muscle and permanently prevent the reflux of stomach acid.
The surgery may also be beneficial for a hiatal hernia, as this condition often contributes to the reflux of stomach acid.
The goal of reflux surgery is to alleviate symptoms, improve quality of life, and provide patients with long-term relief.
Thanks to modern, laparoscopic techniques, the procedure is usually minimally invasive, which allows for rapid healing.

How does reflux develop, and when is surgery necessary?

Reflux disease occurs when the sphincter muscle between the esophagus and the stomach does not function properly, causing stomach contents or gastric juices to flow back into the esophagus.
The most common symptom is heartburn, often accompanied by acid regurgitation or difficulty swallowing. These symptoms are becoming increasingly common in the Western world and can significantly impair quality of life.

In many cases, lifestyle changes—such as eating smaller meals, losing weight, or avoiding acidic foods—as well as medication with proton pump inhibitors (PPIs) to reduce stomach acid production can help.
However, if this conservative treatment does not provide sufficient relief or if the symptoms keep recurring, reflux surgery (fundoplication) is recommended.

RefluxReflux occurs when the sphincter muscle between the stomach and the esophagus does not function properly @ AntonioDiaz /AdobeStock

In this surgical procedure, a portion of the stomach is formed into a cuff that is placed around the lower end of the esophagus. This so-called fundus cuff stabilizes the sphincter and prevents stomach contents from entering the esophagus.
This permanently prevents the reflux of stomach acid, and patients are usually symptom-free again.

Types of Fundus Sleeves Used in Reflux Surgery

Reflux surgery (fundoplication) is now performed almost exclusively as a minimally invasive keyhole procedure (laparoscopic). During the procedure, the surgeon inserts a camera and fine surgical instruments through several small incisions in the abdomen. This minimally invasive surgical technique allows for precise surgical treatment of reflux disease with significantly less pain, minimal blood loss, and faster wound healing.
Patients also benefit from a shorter recovery time and a quicker return to their daily routines.

Nissen-Rosetti Reflux SurgeryThe Nissen anti-reflux surgery is the standard surgical procedure for preventing reflux @ Pepermpron /AdobeStock

Specialized clinics for visceral surgery offer two main types of fundoplication:

1. Nissen fundoplication (full cuff):
This procedure is considered the surgical standard for reflux surgery. In this procedure, the upper part of the stomach (fundus) is completely wrapped around the lower end of the esophagus and sutured in place.
The resulting fundus sleeve reinforces the sphincter and reliably prevents stomach contents from entering the esophagus. Nissen fundoplication is used particularly frequently in patients with severe reflux disease or a hiatal hernia.

2. Toupet fundoplication (partial fundoplication):
In this variant, only part of the stomach is wrapped around the esophagus and secured at the front. This method is particularly suitable for patients with limited esophageal motility or certain underlying conditions such as diabetes.
This surgical procedure also provides a stable reflux barrier, but generally makes swallowing somewhat easier.

Both procedures share the same goal: to permanently prevent the reflux of stomach acid and heartburn and to ensure the long-term success of reflux disease treatment.
Thanks to modern laparoscopic fundoplication, outcomes are now very good in over 90% of cases—many patients report lasting relief from symptoms and complete freedom from symptoms.

When might surgery for reflux be appropriate?

Reflux surgery is recommended when conservative treatments—such as dietary changes or medication with proton pump inhibitors (PPIs)—do not provide sufficient relief from symptoms.
Patients with chronic heartburn, frequent acid regurgitation, or difficulty swallowing—in whom the reflux of stomach acid into the esophagus persists despite treatment—can benefit significantly from surgical treatment (reflux surgery).

Reflux surgery is also frequently performed in combination with hiatal repair for a hiatal hernia—a gap in the diaphragm through which part of the stomach slides upward. In this procedure, the diaphragm is surgically reconstructed and the junction between the esophagus and the stomach is stabilized.
This combination eliminates the anatomical cause of the reflux of stomach contents into the esophagus and enables most patients to live symptom-free permanently after reflux surgery.

In experienced clinics specializing in visceral surgery, a decision is made on a case-by-case basis as to which surgical procedure—such as Nissen fundoplication or Toupet fundoplication—is best suited for the individual patient.
Modern minimally invasive procedures are now considered safe and effective, particularly for patients undergoing reflux surgery who are seeking a long-term solution to reflux disease.

What are the risks associated with reflux surgery?

As with any surgical procedure, certain risks and side effects can occur with reflux surgery (fundoplication). However, thanks to modern laparoscopic techniques and experienced surgeons, complications are rare.
The most common symptoms in the first few days after reflux surgery include:

  • Swelling or pain around the surgical incision
  • A feeling of fullness or temporary pressure in the upper abdomen
  • Difficulty swallowing, belching, or vomiting due to the digestive system readjusting
  • Bruising or minor postoperative bleeding around the sutures
  • Wound infections or irritation in the surgical area
  • In rare cases: injury to the diaphragm, esophagus, stomach, or other adjacent organs

These side effects usually subside after a few days to weeks. Thanks to the minimally invasive, gentle surgical technique, the risk of serious complications is extremely low today.
Specialized centers for visceral surgery place great emphasis on safe surgical procedures, ensuring that treatment for reflux disease is successful in over 90% of cases.

Prognosis for Reflux Surgery

Reflux surgery is a successful method for permanently curing reflux disease. According to a study, it is more successful in the long term than drug therapy. 

For younger patients, reflux surgery offers a cost advantage over long-term (permanent) medication. Approximately 90% of patients who undergo reflux surgery no longer experience reflux or heartburn after the procedure.

In 8% of patients, reflux surgery is unsuccessful. In these cases, the sleeve cannot stop the reflux. 

It is not uncommon for patients to complain of aftereffects of the procedure despite successful reflux surgery, such as:

  • a feeling of fullness
  • Difficulty belching
  • Vomiting

Prognosis and Success Rates of Reflux Surgery

Reflux surgery (fundoplication) is currently one of the most effective procedures for treating gastroesophageal reflux disease (GERD). It is usually performed under general anesthesia and is considered a permanently effective surgical treatment when acid blockers or proton pump inhibitors do not provide sufficient relief.
In many patients, heartburn persists despite conservative treatment, or symptoms return after discontinuing the medication.

During reflux surgery, the upper part of the stomach is wrapped around the esophagus in such a way that the esophageal sphincter is strengthened and the backflow of stomach acid into the esophagus is permanently prevented.
As a result, stomach contents can no longer flow upward, which reliably eliminates typical symptoms such as heartburn, difficulty swallowing, and acid regurgitation.
The goal of the surgery is to prevent the reflux of stomach contents into the esophagus and to restore the natural reflux barrier.

Long-term studies show that approximately 90% of patients are symptom-free after reflux surgery. The procedure is particularly beneficial for severe heartburn or a hiatal hernia, as it addresses the anatomical cause and enables long-term healing.
In specialized clinics for visceral surgery, the procedure is performed laparoscopically—that is, using a minimally invasive approach—which requires only small incisions in the abdominal wall. The surgery is generally gentle and safe, with a short recovery time and significantly fewer postoperative symptoms.

About a week after surgery, most patients are largely back to their normal activities. A gastroscopy can be performed after a few months to monitor healing.
Compared to medication, reflux surgery offers a lasting solution because it addresses the root cause of the condition rather than merely alleviating the symptoms of heartburn.

For many patients, reflux surgery means a significant improvement in quality of life—they can eat, lie down, and sleep normally again without stomach contents flowing back into the esophagus.
The treatment of their reflux disease is thus permanently successful, and with proper follow-up care, most patients remain symptom-free in the long term.

FAQ: Frequently Asked Questions About Reflux Surgery

Reflux surgery is recommended when taking acid blockers or proton pump inhibitors does not sufficiently relieve symptoms such as heartburn. Especially in cases of a hiatal hernia or persistent gastroesophageal reflux, surgical treatment can eliminate the anatomical cause and permanently strengthen the esophageal sphincter.

How is reflux surgery performed?

Reflux surgery is typically performed laparoscopically (minimally invasively) under general anesthesia. During the procedure, the surgeon wraps the upper part of the stomach around the esophagus to prevent reflux. This procedure—known as fundoplication—restores the natural reflux barrier and prevents stomach contents from flowing back into the esophagus.

How long does recovery take after reflux surgery?

Recovery is usually quick: Many patients can resume their daily routines as early as about one week after surgery. Full recovery is usually achieved within a few weeks. A gastroscopy may be performed to check the surgical outcome and ensure that the esophagus remains free of inflammation.

How effective is reflux surgery for chronic heartburn?

Reflux surgery has very good long-term results. Studies show that about 90% of patients are symptom-free after surgery. Fundoplication permanently prevents the backflow of stomach acid and thus offers an effective treatment for reflux disease, especially in cases of severe heartburn or recurrent reflux despite medication.

Where should reflux surgery be performed?

It is recommended that the procedure be performed at a specialized clinic for visceral surgery. There, experienced surgeons have a high level of expertise in laparoscopic fundoplication and follow standardized procedures. This ensures that the reflux surgery is performed in a particularly gentle and safe manner—with the best prospects for a long-term, symptom-free life.

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About the medical author

Dr. rer. nat. Marcus Mau

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Sources
Bergmann H et al., Die laparoskopische Fundoplicatio nach Nissen-deMeester und Toupet im retrospektiven Vergleich. https://link.springer.com/chapter/10.1007/978-3-642-55715-6_121?error=cookies_not_supported&code=92dd19a1-3e23-4e63-9f64-34608bd14e3c
flexikon.doccheck.com/de/Fundoplikatio
Fuchs K-H. Stellenwert der laparoskopischen Fundoplicatio. Dtsch Arztebl 1998; 95(40): A-2466 / B-2108 / C-1974
gesundheitsinformation.de/wie-wird-reflux-behandelt.html
Grant AM et al., Minimal access surgery compared with medical management for gastro-esophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX). BMJ 2013; 346: f1908
pschyrembel.de/Fundoplicatio/K089T
sodbrennen.de/hilfe-sodbrennen/operation/

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