Breast biopsy - find a specialist and information

Leading Medicine Guide Editors
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Leading Medicine Guide Editors

A breast biopsy is a removal of tissue from the breast. Your doctor uses it to clarify whether changes in your breast are a tumor or just a cyst. A lump in your breast does not automatically mean breast cancer. Mammography, ultrasound and MRI allow your doctor to make a suspected diagnosis. He will confirm this by taking a tissue sample. Only a biopsy and a histological examination of the sample taken will allow a reliable diagnosis of breast cancer to be made.

Below you will find further information on the examination and specialists for a breast biopsy.


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Article overview

Breast biopsy procedure

Your doctor has various procedures available for taking tissue samples. As a rule, he will use minimally invasive methods such as punch or vacuum biopsy.

Very rarely, he will resort to a surgical or open biopsy. Which procedure is used in your case depends on the following questions:

  • Is the lump palpable?
  • Is the lump clearly visible in the ultrasound image?
  • Do microcalcifications detected in the mammogram require a detailed examination?

Depending on this, the following procedures are used:

  • Punch biopsy (high-speed punch biopsy)

If the lump is palpable or clearly visible on ultrasound (solid-appearing findings), the doctor performs a punch biopsy as standard.

He shoots a 1.5 millimeter thick hollow needle into the suspicious breast area under ultrasound guidance and at high speed (high-speed punch) .

He takes three to five small, cylindrical punches at different points. He punctures the skin only once. The procedure is painless and leaves no scar. You will be given a local anesthetic during the procedure.

StanzbiopsiePunch biopsy is the standard method for removing tissue from lumps and foci @ ST.art /AdobeStock

  • Fine-point needle puncture

To examine the lymph nodes, the doctor removes cells from the lymph node using a wafer-thin hollow needle (fine needle aspiration).

  • Vacuum biopsy

Vacuum biopsy is used to take larger tissue samples.

During a vacuum biopsy, the doctor uses a 3.5 millimeter thick hollow needle. With the help of mammography, ultrasound or MRI monitoring, he sucks out around 20 tissue samples. These are then cut off with a tiny rotating knife.

A computer calculates the exact path of the needle to ensure that the tissue is removed safely.

The procedure takes longer than a punch biopsy. As the doctor takes a comparatively large tissue sample, the diagnostic reliability is very high.

He can then X-ray the tissue sample to detect microcalcifications in the breast. Microcalcifications are usually harmless, but can indicate benign diseases or breast cancer.

  • Surgical or open breast biopsy

If minimally invasive procedures do not provide clear results, the doctor will perform a surgical biopsy. A surgical breast biopsy is very rarely necessary today.

To find the abnormal tissue, the surgeon marks the suspicious areas in advance with a thin wire. For localization, he uses mammography, MRI or ultrasound monitoring. If the lump is palpable, the doctor marks the suspicious area with a colored pen.

In an open breast biopsy, the doctor removes the tissue change partially (incisional biopsy) or completely (excisional biopsy). The doctor usually cuts out the suspicious area completely. The patient is under general anesthesia during this procedure .

What happens after the breast biopsy

A pathologist then examines the tissue removed under a microscope and assigns it to this B classification:

  • B1: normal
  • B2: benign (e.g. cyst)
  • B3: benign, but not sure how the change will develop further
  • B4: suspected malignant change (requires clarification)
  • B5: malignant, invasive, growing tumor that requires treatment
Laboruntersuchung nach Brust-BiopsieA specialized laboratory analyses the tissue samples taken @ luchschenF /AdobeStock

    The classification does not yet represent a final diagnosis. However, it does determine what measures the gynecologist should subsequently take.

    If the findings are benign (B2), your doctor will decide how to proceed depending on your symptoms. If the lump bothers you, the doctor can remove it surgically. Otherwise, you will need to have it checked regularly to detect any changes at an early stage.

    If there is a suspicion of cancer or a tumor in the breast that requires treatment, the doctor will remove it by means of an open biopsy.

    In order to find the area again, a marker clip is attached during the breast biopsy (regardless of whether it is a punch or vacuum biopsy). This can also remain in the breast if no further measures are required.

    In the case of cancer, the doctor will order further examinations. This is because not all breast cancers are the same. The individual tumors differ in terms of their characteristics.

    The doctor uses the information obtained to compile a "tumor profile". The specialist clinic then decides on the treatment based on the "tumor profile".

    Aftercare following breast biopsy

    Aftercare depends on the breast biopsy procedure.

    Minimally invasive methods do not require any special aftercare. The doctor will discuss the findings with you in detail. He will also inform you about the necessary treatment measures.

    An open biopsy requires an outpatient or short inpatient stay. The procedure leaves a scar inside the breast, which makes mammographic assessment of the breast more difficult.

    Complications and side effects of breast biopsy

    Vacuum and punch biopsies are minor surgical procedures with few complications or side effects.

    These include:

    • Allergic reactions to the anesthetics used
    • bleeding
    • Bruising
    • Nerve damage
    • Excessive scarring

    The breast is also sensitive to pressure in the first few days after the operation . The slight pain subsides as soon as the wound heals. There is no risk of tumor cells being carried over or activated by the breast biopsy.

    You should pay attention to this after the breast biopsy

    • Do not drive for 24 hours after the tissue has been removed
    • Do not operate any dangerous equipment
    • Alsoavoid strenuous activities such as sports or house cleaning
    • Do not shower until the following day.
    • Avoid bathing, swimming and saunas for 10 days

    Conclusion

    A breast biopsy is a minor procedure with a low risk of complications. It provides you and your doctor with clarity as to whether the changes in your breast are benign or malignant. Your doctor can then decide what treatment is required.

    References

    Duda./Köhler (2017): Vakuumbiopsie. In: Duda, V. F./Schulz-Wendtland, R. (Hrsg.): Mammadiagnostik. Komplementärer Einsatz aller Verfahren. Berlin: Springer, S. 150-153.

    Duda/Köhler (2017): Hochgeschwindigkeitsstanzbiopsie. In: Duda, V. F./Schulz-Wendtland, R. (Hrsg.): Mammadiagnostik. Komplementärer Einsatz aller Verfahren. Berlin: Springer, S. 147-150.

    Fallenberg/Gerber (2021): Diagnostik und Therapie früher und fortgeschrittener Mammakarzinome: Früherkennung und Diagnostik. (URL: https://www.ago-online.de/fileadmin/ago-online/downloads/_leitlinien/kommission_mamma/2021/Einzeldateien/2021D_03_Frueherkennung_und_Diagnostik_MASTER_final_20210302.pdf).

    Fehm et al. (2017): Brustkrebs: Biopsie. (URL: https://www.krebsgesellschaft.de/onko-internetportal/basis-informationen-krebs/krebsarten/brustkrebs/diagnose/diagnoseverfahren-biopsie.html).

    Kreipe/Maass (2021): Diagnostik und Therapie früher und fortgeschrittener Mammakarzinome: Läsionen mit unsicherem biologischen Potenzial (B3). (URL: https://www.ago-online.de/fileadmin/ago-online/downloads/_leitlinien/kommission_mamma/2021/Einzeldateien/2021D_06_Laesionen_unsicheres_Potential_MASTER_final_20210301.pdf).

    Stiftung Deutsche Krebshilfe (2019): Die blauen Ratgeber: Brustkrebs – Antworten, Hilfen, Perspektiven. (URL: https://www.krebshilfe.de/infomaterial/Blaue_Ratgeber/Brustkrebs_BlaueRatgeber_DeutscheKrebshilfe.pdf).

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