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Disease · General Gastroenterology

Stomach Disorders – Common Diseases of the Stomach and Intestines

Brief overview — the essentials first

Stomach disorders are common and include both acute and chronic conditions affecting the stomach lining and stomach wall. Typical symptoms include heartburn, nausea, or loss of appetite, and in some cases, diarrhea or abdominal pain. A Helicobacter pylori infection can cause gastritis or a gastric ulcer in the duodenum. If symptoms persist, a gastroscopy should be performed to rule out malignant cancers such as gastric carcinoma.

Stomach disorders are among the most common diseases of the gastrointestinal tract and affect people of all ages. A typical disorder can be acute or chronic and cause various symptoms such as nausea, vomiting, or a feeling of fullness. The most common stomach disorders include gastritis, stomach ulcers, and stomach cancer. These conditions often involve inflammation of the stomach lining, which is triggered by the bacterium Helicobacter pylori or by excessive production of stomach acid.

Heartburn resulting from gastroesophageal reflux disease also frequently affects the esophagus and the stomach. Some stomach disorders initially present without noticeable symptoms and are only detected during a gastroscopy. Early diagnosis is important, as some conditions can be malignant or lead to bleeding and ulcers.

Definition: Stomach Disorders

Symptoms in the stomach area are part of the spectrum of gastrointestinal disorders. These include all conditions that affect the digestive tract, of which the stomach is a part. 

Stomach disorders often manifest as abdominal pain, particularly in the upper abdomen, where the stomach is located. For affected patients, these symptoms are unpleasant and often painful.

If you have stomach symptoms that do not go away or recur regularly, it is advisable to see a doctor. A gastroenterologist is the specialist responsible for treating stomach disorders.

Gastroenterology (from ancient Greek: gastēr = stomach, énteron = intestine) is a branch of internal medicine. It covers, among other things, the gastrointestinal tract, the liver, and the pancreas.

Stomach painStomach pain is usually harmless, but sometimes it can indicate a serious illness @ ipopba /AdobeStock

Symptoms of Stomach Disorders

The stomach can produce a wide variety of symptoms that tend to be nonspecific in nature. Often, symptoms appear that are not caused by any underlying disease, such as a feeling of fullness after a heavy meal. 
Furthermore, nausea and vomiting are common symptoms of a short-term gastrointestinal infection and are usually temporary.

If your symptoms are long-term or recurring, serious conditions may be to blame, such as:
  • Ulcerative colitis (chronic inflammation of the large intestine)
  • Inflammation of the stomach lining (acute gastritis, chronic gastritis)
  • Ulcer (benign or cancerous)
  • Inflammation of the esophagus
  • Crohn’s disease (chronic inflammation of the intestines)
  • Irritable stomach (digestive disorder in the upper abdomen)

If you experience regular nausea, fatigue, abdominal cramps, vomiting, or diarrhea, it is advisable to see a specialist for evaluation and diagnosis.

Causes and Risk Factors of Stomach Disorders

Due to the wide variety of possible causes of stomach disorders, it is not possible to clearly pinpoint specific causes. 
Inflammation of the mucous membrane has a different underlying cause than gastroenteritis. Heartburn (stomach burning) also cannot be compared to irritable stomach, which is usually caused by impaired digestion. Pathogens are often responsible, including the Helicobacter pylori bacterium in cases of mucosal inflammation.

While many conditions are curable, there are inflammatory processes that stem from chronic conditions with no known cause. These are incurable. 
These include Crohn’s disease, which is characterized by regular flare-ups.


Risk factors include:

  • A genetic predisposition 
  • A compromised immune system
  • Advanced age 
  • Side effects from medications
In addition, certain lifestyle factors are known to be problematic. 

These include:

  • Heavy alcohol consumption
  • Smoking and
  • Frequent consumption of heavily smoked and grilled foods, as well as foods that are very high in salt

Alcohol and cigarettes increase the risk of stomach diseasesAlcohol and cigarettes increase the risk of stomach diseases @ exclusive-design /AdobeStock

Examination and Diagnosis of Stomach Disorders

The examination for a stomach disorder depends on the symptoms. Your doctor will first ask you about the nature and frequency of your symptoms and, if necessary, perform a physical examination. 

To make an accurate diagnosis, they have various options available, such as imaging procedures. These provide insight into what is happening inside the stomach.

Typical diagnostic options include:

If necessary, your treating physician will take a tissue sample and order laboratory tests.

During a gastroscopy, your doctor can identify pathological changes, including inflammation and ulcers. In cases of unexplained abdominal pain, it is often advisable to combine this with an X-ray of the abdomen. 
In an acute emergency, CT and MRI provide reliable information and offer the necessary guidance for the next steps.

Treatment of Stomach Disorders

The treatment of your stomach symptoms depends primarily on the underlying causes and the diagnosed condition:
In cases with benign causes, stomach-protecting medication is often sufficient. Your doctor may choose not to prescribe medication, such as in cases of mucosal inflammation, which often heals on its own. 
If you have Type A gastritis, which is chronic and autoimmune in nature, vitamin B12 injections can help. If bacteria are the cause of the inflammatory process, your doctor may prescribe an antibiotic.
Targeted treatment to eliminate the underlying cause (eradication therapy) is also one of the more common treatments. Medication to reduce stomach acid is another option. If you have gastritis, you should minimize harmful factors (such as alcohol) to give your stomach a break.

In the case of a malignant tumor (stomach cancer), surgery is the primary treatment. The goal is to completely remove the tumor in order to achieve a permanent cure. 
Your treating physician—in this case, a medical oncologist—will recommend chemotherapy or, as a complementary treatment, radiation therapy as the next steps.

Course and Prognosis of Stomach Diseases

The course of stomach diseases depends on the type of condition. A gastrointestinal infection, a benign stomach ulcer, or a non-chronic form of gastritis heals quickly and completely. 
Chronic conditions that do not disappear completely can be managed much more gently through targeted treatment tailored to your individual situation. 
The goal here is to alleviate flare-ups and reduce the associated symptoms. How effective a particular method is also depends on your medical history and cannot be answered in general terms.

With stomach cancer, the earlier the doctor detects the disease, the better the prognosis. If the disease is untreatable, your doctor will ensure that you maintain a high quality of life for as long as possible.

Conclusion

There are many conditions affecting the stomach and the digestive system. Most of them are temporary in nature and arise, for example, as a result of an infection or an overly large meal. 
If symptoms persist, are accompanied by chronic pain, or if you’re experiencing unexplained symptoms, you should consult a gastroenterologist.

FAQ

What are the most common stomach disorders?

The most common stomach disorders include gastritis, chronic gastritis, peptic ulcers, and gastroesophageal reflux disease (GERD). These are among the most common disorders of the gastrointestinal tract and are often caused by Helicobacter pylori. Stomach cancer, or gastric carcinoma, is also one of the serious—albeit rarer—diseases of the stomach.

What are the symptoms of stomach disorders?

Typical symptoms include nausea, vomiting, bloating, loss of appetite, and heartburn. Depending on the condition, bleeding, diarrhea, or pressure in the stomach may also occur. Some conditions often cause no symptoms and remain undetected for a long time.

What role does Helicobacter pylori play?

The bacterium Helicobacter pylori—or a Helicobacter pylori infection—can trigger inflammation of the stomach lining. An infection with Helicobacter pylori can cause chronic gastritis, ulcers, or open sores in the stomach. In addition, Helicobacter pylori can contribute to the development of stomach cancer and increase the risk of malignant tumor formation.

How are stomach disorders diagnosed?

Diagnosis involves taking a medical history, performing a physical examination, and often conducting a gastroscopy. During the procedure, a tissue sample can be taken from the stomach lining to detect inflammation, an ulcer, or malignant tissue changes. A Helicobacter pylori infection can also be detected in this way.

Can stomach diseases become chronic?

Yes, many conditions can become chronic, particularly chronic gastritis or long-term reflux disease. If left untreated, they can damage the mucosa, impair the stomach’s acid defense, and cause problems throughout the entire gastrointestinal tract. Therefore, persistent symptoms should be evaluated by a doctor at an early stage.

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Sabine Schneider

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Sabine Schneider – medical author: Explore expert articles and medical expertise in the Leading Medicine Guide.

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Sources

https://www.ndr.de/ratgeber/gesundheit/Gastritis-Symptome-erkennen-und-behandeln,gastritis100.html

https://www.magen-darm-ratgeber.de/magen-bauch/krankheiten/

https://www.internisten-im-netz.de/fachgebiete/magen-darm/haeufige-erkrankungen.html

https://www.gastro-liga.de/ratgeber/ratgeber-magen/

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