Multiple pregnancy - specialists and information on complications and prevention

Leading Medicine Guide Editors
Author
Leading Medicine Guide Editors

In a multiple pregnancy, several children grow in the uterus at the same time. Pregnancies with multiples are a particular challenge for the mother and the unborn children. Complications during pregnancy or birth occur more frequently than with singleton pregnancies. Intensive care by specialists in gynecology and obstetrics is very important in a multiple pregnancy. Find out more here and find selected specialists!

ICD codes for this diseases: O30, O31

Recommended specialists

Article overview

What is a multiple pregnancy?

If a woman is pregnant with more than one embryo in her uterus, this is called a multiple pregnancy. Depending on how many embryos there are, this is referred to as a twin, triplet, quadruplet or sextuplet pregnancy.

Identical and fraternal twins can develop:

Identical twins develop from a fertilized egg cell (zygote). Both embryos are genetically identical. They are of the same sex. A monozygotic twin pregnancy is also called a monozygotic pregnancy (mono = only).

Fraternal twins develop from two fertilized (different) egg cells. Experts call this form a dizygotic pregnancy (di = two). Although both eggs mature in the ovaries at the same time, they come from two different sperm. The siblings are genetically different.

One third of multiple pregnancies are identical (monozygotic) twins. The remaining two thirds are fraternal (dizygotic) twin pregnancies.

Neugeborene Zwillingsbuben.
Newborn twin boys @ Vad-Len / AdobeStock

Types of identical multiple pregnancies

Because identical multiples can be attached to the uterus in different ways, they have different names:
  • Dichoriale-diamniot: each embryo is in its own amniotic sac (amniotic cavity) with its own amniotic cavity (chorionic cavity). Each twin has its own placenta.
  • Monochoriale-diamniot: The identical twins have their own amniotic sac (amniotic cavity). They have a common amniotic cavity (chorionic cavity) and share a placenta.
  • Monochorial monoamniotic: The multiples are in a common amniotic sac (amniotic cavity) and a common amniotic cavity (chorionic cavity). In this case, the twins can grow together (conjoined twins) if the division processes do not take place correctly. This occurs in less than 0.5% of cases of identical twin pregnancies.
Siamesische Zwillinge
Conjoined twins @ lunamarina /AdobeStock
Each form offers the unborn children different developmental conditions. This is why doctors must closely monitor the pregnancy so that they can closely observe the development of the unborn children.

Why do multiple pregnancies occur?

Multiple pregnancies with two or more embryos usually occur after hormone treatment. The hormones administered during fertility treatment stimulate the ovaries more strongly, allowing several eggs to mature.

Multiple pregnancies often occur after artificial insemination (in vitro fertilization, IVF, ICSI). Doctors insert one, two or a maximum of three fertilized eggs into the uterus of the expectant mother.

The primary aim of fertility treatment is to increase the probability of pregnancy. This is why doctors and expectant mothers accept the risk of a multiple pregnancy.

Multiple pregnancies are - without hormonal support - very rare. Natural factors are the increasing age or a genetic predisposition of the mother. For example, if the mother is a multiple herself.

First signs of a multiple pregnancy

  • An increased level of the pregnancy hormone HCG (human chorionic gonadotropin)
  • Morning sickness with vomiting in the first weeks of pregnancy
  • Significant weight gain in the first trimester (1st to 12th week of pregnancy),
  • A significantly enlarged abdominal circumference and
  • A significantly enlarged uterus. The gynaecologist can feel this or detect it on ultrasound.
Frau mit Babybauch (Zwillingen)
Woman with baby bump (twins) @ Uwe Grötzner / AdobeStock

Diagnosis of a multiple pregnancy

A multiple pregnancy is diagnosed between the eighth and twelfth week of pregnancy using ultrasound (sonography).
Schwangerschaftsdiagnostik mittels Ultraschall
Pregnancy diagnosis using ultrasound @ Alexander Raths / AdobeStock

The examinations during a multiple pregnancy

The general check-ups during pregnancy include

  • Checking the blood group, haemoglobin and urine
  • Regular measurement of body weight, abdominal girth and blood pressure (RR)
  • Inspection of the size of the uterus
  • Examination of the pelvis and cervix
Pregnancies with multiples are high-risk pregnancies. This means that they have an increased risk of complications during pregnancy and birth.
For this reason, women who are pregnant with multiples should have more frequent medical check-ups. Every 14 days up to the 28th week of pregnancy and weekly thereafter. The examinations are carried out using CTG (cardiotocography). The CTG is a device with which doctors can record the heart rate of the unborn baby and the contractions.

The most common pregnancy complaints:

With multiple pregnancies, the usual pregnancy symptoms occur in an intensified form:

  • Severe nausea with frequent vomiting
  • Water retention (congestive edema) and tingling in the legs from the 14th week of pregnancy onwards
  • Back pain due to weight gain
  • Breathlessness (due to pressure of the multiples on the lungs)
  • Strong kicks and bumps against the abdominal wall
  • General restlessness and restlessness
Schwangere Frau mit Rückenschmerzen
Pregnant woman with back pain @ Nutlegal / AdobeStock

The most common pregnancy complications

  • Hyperemesis gravidarum: frequent vomiting
  • Pre-eclampsia: High blood pressure with protein excretion in the urine
  • Increased risk of premature birth: A birth that takes place before the 37th week of pregnancy is referred to by doctors as a premature birth. Signs of a premature birth include premature contractions, premature rupture of the membranes or a severely shortened cervix (uterine cervix) of less than 3 centimetres
  • Acute or chronic placental insufficiency: The exchange of substances and blood flow are insufficient. This can result in damage to the fetus or fetuses.
  • Reduced growth or shrinkage of the fetus (hypotrophy)
  • Neurological damage to the fetus or fetuses: In the event of a reduced oxygen or nutrient supply
  • Miscarriage (abortion): If the pregnancy ends before the 23rd or 24th week of pregnancy. At this point, the children are not yet viable. The first examinations by the pediatrician are important to determine the developmental status of the fetuses after a multiple pregnancy.
  • Feto-fetal transfusion syndrome: Occurs in twin pregnancies when the two fetuses share a placenta in the womb. The problem with the condition is that the blood flow between the two fetuses is unevenly distributed. While one receives too much blood, the other receives too little. Both are damaged. Laser ablation can help in this case. Laser ablation uses a laser to obliterate the vascular connections within the placenta. This procedure is risky. Therefore, only specialized centers should perform laser ablation.
Gebärende Frau, der Mann hält ihre Hand.
Woman giving birth, the man holding her hand @ Gorodenkoff / AdobeStock

Emergency signs during a multiple pregnancy

If the following symptoms occur during a multiple pregnancy, please take them seriously and contact a doctor immediately:

  • Contractions: these indicate that labor is about to begin.
  • Bleeding: If you experience bleeding, please call the emergency services immediately.
  • Abdominal pain: Should be checked by a doctor as soon as possible.
  • Fever: Indicates an infection or other complication.
  • Severe pain in one leg or in the legs: May indicate a leg vein thrombosis.
  • A decrease in the baby's movements: Should be urgently checked by a doctor.
  • Leakage of amniotic fluid
  • Burning pain when urinating: Indicates a urinary tract infection requiring treatment.
  • Deteriorating general condition due to pre-eclampsia (increased blood pressure and abnormal protein excretion in the urine).
  • Signs of eclampsia (seizure)
Schwangere Frau mit Schmerzen
Pregnant woman with pain @ KAMPUS /AdobeStock

Possible birth complications

There is also an increased risk of multiple pregnancies during birth.

The following complications can occur:

  • A prolonged opening phase of more than twelve hours.
  • Premature placental abruption after the birth of the first twin.
  • An umbilical cord prolapse: in which vital blood vessels in the umbilical cord are pinched off. This results in hypoxia of the child.
  • Heavy post-partum bleeding: Due to reduced contractions of the uterine muscles (uterine atony).

Treatment and care for multiple pregnancies

If you are pregnant with multiples, avoid stress and physical exertion. The primary aim of a multiple pregnancy is to maintain the pregnancy for a long time.

Women who go into labor before the 34th week of pregnancy or who suffer from cervical insufficiency (opening of the cervix) are given medication such as tocolytics or corticosteroids. Corticosteroids are drugs that accelerate the maturation of the unborn child's lungs. They are usually used for premature births.

The birth plan

The birth plan contains all the important information about the pregnancy and delivery. It also documents the state of health of the unborn children and the mother.

For example:

  • Is a natural vaginal birth possible?
  • Has pain relief been administered?
  • Is a caesarean section planned?

As a natural birth is complicated and risky in the case of multiple pregnancies, doctors usually perform a caesarean section ( caesarean section).

References

  • https://www.dggg.de/leitlinien-stellungnahmen/leitlinien/
  • https://www.dgkj.de/eltern/spezialisten-portraits/neonatologie/
  • Dr. med. Sabine Schmidt und Dr. med. Arne Schäffler: Lehrbuch für Pflegeberufe, Ärzte und Patienten. Medizin und Gesundheit. Köln: Naumann & Göbel Verlagsgesellschaft, 2003
  • https://www.aerzteblatt.de/archiv/78411/Perinatale-Probleme-von-Mehrlingen
  • https://flexikon.doccheck.com/de/Mehrlingsschwangerschaft
Whatsapp Facebook Instagram YouTube E-Mail Print