The lymphatic system: information & doctors for the lymphatic system

Leading Medicine Guide Editors
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Leading Medicine Guide Editors

The lymphatic system is an important part of the immune system. The finely branched network runs parallel to the blood vessels like a canal system. It removes excess substances and at the same time filters out pathogens and foreign particles. This is why the lymph nodes swell in some diseases.

Here you will find further information and selected doctors for diseases of the lymphatic system.

Article overview

What are lymphs?

The word lymph comes from the Latin "lympha", which means "clear water". In fact, lymph is a watery, yellowish-colored substance. It flows through the entire body in meter-long, very fine channels.

Lymph is formed from nutrient-rich blood plasma. When it passes from the arterial to the venous blood vessels, around 10 percent of the blood plasma remains in the intercellular spaces. That is about two liters per day. These remnants are referred to as tissue fluid.

A parallel network: the lymphatic vessels

Wafer-thin lymphatic capillaries begin everywhere in the intercellular spaces of the body. They absorb the tissue fluid that remains there and transport it further towards the heart as lymph. There it is reunited with the blood in the superior vena cava.

The initially very branched lymphatic capillaries merge to form larger lymphatic vessels. These usually run parallel to the venous blood vessels. Parts of these vessels, the so-called lymphatic hearts, contract about ten times a minute through muscle contraction. In this way, they provide the necessary pumping movement.

Das Lymphsystem im menschlichen Körper
The lymphatic system runs through the entire body. A lymph node is also shown here © lom123 | AdobeStock

The lymph nodes

In certain places, for example

  • under the armpit,
  • on the neck and
  • in the groin,

the lymph vessels are interrupted in the form of nodes. Here the lymph from

  • pathogens,
  • cell debris and
  • foreign bodies

to protect the organism from damage.

The lymph nodes, which are around 1-20 mm in size, are lymphatic organs. They contain lymphocytes and macrophages. These are special immune cells belonging to the white blood cells that recognize and attack viruses and bacteria.

The lymph nodes in the neck can become palpable during a viral flu, for example. This is because the infection causes them to increase their output and swell accordingly.

Lymphkapillaren zwischen den Blutgefäßen
Embedding of lymphatic capillaries (green) between the blood vessels © ilusmedical | AdobeStock

Other lymphatic organs

In addition to the lymph nodes, the system also includes other lymphatic organs. Lymphocytes can multiply or differentiate in these organs. They complement each other in their functions:

The bone marrow

This is where it all begins. Lymphopoiesis takes place in the bone marrow, where lymphocyte stem cells first develop into lymphoblasts. These in turn give rise to two types of lymphocyte precursors:

  • Pro-T lymphocytes and
  • pro-B lymphocytes.

They pass through the bone marrow and then settle in the various other lymphatic organs.

The thymus

In the thymus, the pro-T lymphocytes coming from the bone marrow are transformed into T lymphocytes.

They first undergo selection and then imprinting, which prepares them for their important role in the immune system.

The spleen

Among other things, the spleen produces the aforementioned macrophages (also known as defense or scavenger cells ). It also stores lymphocytes and breaks down outdated blood cells.

The tonsils or lymphatic ring

The lymphatic ring consists of the tonsils in the throat, tongue and palate. It destroys pathogens that want to spread in the body from the air we breathe and via the mucous membranes.

B lymphocytes also multiply in the tonsils.

Lymphoid tissue in the intestine (Peyer's plaques)

Peyer's plaques are also known as Peyer's patches or Peyer's glands. They are found in the mucous membrane of the small intestine up to the appendix.

They consist of an accumulation of microscopically small colonies of B lymphocytes, so-called lymphoid follicles. They make an important contribution to the intestinal defense against infection and transmit immunological information.

The tasks of the lymphatic system summarized

  1. It is an important part of the immune system.
  2. It regulates the volume of fluid in the tissue.
  3. It transports dietary fats from the abdominal cavity directly to the cells.

Lymphoedema diseases - symptoms and treatment

Lymphoedema: drainage disorder of the lymphatic system

If the lymph flow is disturbed or interrupted, this leads to increased fluid accumulation in the tissue. Such lymphoedema usually occurs in the extremities.

The affected body region swells and the subcutaneous fatty tissue develops a doughy consistency. If left untreated, this can lead to

with corresponding functional impairment.

The only remedy here is regular manual lymphatic drainage. A masseur stimulates the vascular system with light, circular movements. This allows the lymph to drain better.

Lymphangitis: inflammation of a lymph vessel

Inflammation of lymph vessels usually occurs in one of the superficial lymphatic vessels. In the affected region, the skin reddens and a red cord spreads from the focus of inflammation towards the center of the body. The area is usually painful and slightly swollen.

If lymphangitis is caused by bacteria, it can be treated with antibiotics. See a doctor in good time! Otherwise it can lead to complications, in the worst case even to blood poisoning (sepsis).

Hodgkin's lymphoma and other cancers

In addition to viruses and bacteria, lymph nodes also filter out tumor cells in the event of cancer. These accumulate in the node and then gradually spread throughout the body via the lymphatic system.

To prevent this, the doctor can remove individual lymph nodes located near a tumor.

Other cancers such as

directly affect the lymphatic system. In malignant lymphomas, the lymph nodes typically swell. They occur in different forms and are treatable to varying degrees.

Das Lymphsystem und insbesondere die Achsellymphknoten
In breast cancer, the lymph nodes in the armpits swell (so-called sentinel lymph nodes) © Henrie | AdobeStock

Conclusion on the lymphatic system

Swollen lymph nodes are a serious sign of illness, but no reason to panic. They often occur with common colds or also with mononucleosis.

See a doctor if

  • the swelling does not go down after a few days,
  • you have severe symptoms or
  • you suspect blood poisoning after an injury.
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