Specialist · Foot Surgery and Ankle Surgery
Prof. Dr. med. Markus Knupp
Specialist in ankle osteoarthritis, prosthetics, and ankle joint fusions in Basel
Mein Fusszentrum AG· Allschwilerstrasse 14, 4055 Basel

Prof. Dr. med. Markus Knupp is an internationally recognized specialist in ankle disorders and surgical procedures involving the ankle joint. His primary focus is the treatment of ankle osteoarthritis, including the use of ankle prostheses, total ankle replacements, and ankle arthrodesis (joint fusion).
With state-of-the-art techniques and years of experience, he offers individualized, evidence-based treatment plans tailored to each patient’s needs.
Areas of focus
- Treatment of Ankle Osteoarthritis (Ankle Arthrosis)
- Implantation of ankle prostheses / total ankle replacements
- Performance of ankle joint fusions (arthrodesis)
- Revision surgeries: conversion from fusion to prosthesis and vice versa
- Complex reconstructive procedures on the ankle joint
- Use of advanced techniques such as 3D surgical planning and patient-specific instrumentation
Admission criteria
- At least 10 years of surgical and treatment experience
- Expertise in modern diagnostic and surgical procedures
- An outstanding treatment focus within your own specialist area
- Member of a leading national professional association
- Leading professional position
- Active participation in specialist events (e.g. lectures)
- Active in research and teachin
- Evaluated quality management (e.g. certification)
- Member of a specialist society (e.g. GFFC, DAF) (Fußchirurgie und Sprunggelenkchirurgie)
About Prof. Dr. med. Markus Knupp
Prof. Dr. med. Markus Knupp is an internationally recognized foot and ankle surgeon and one of the leading experts in ankle osteoarthritis.
With over 20 years of surgical experience and several thousand successful procedures, he specializes in the treatment of degenerative conditions of the ankle joint. His focus lies in carefully balancing joint-preserving treatments and surgical interventions, tailoring each approach to the individual needs of patients with ankle osteoarthritis.
A particular emphasis is placed on total ankle replacement. Prof. Knupp performs ankle prosthesis implantation using the latest technologies, including precise 3D planning and patient-specific instrumentation. These methods enable anatomically accurate and long-lasting solutions for advanced stages of arthritis. Alternatively, he offers ankle arthrodesis (joint fusion), which remains a proven treatment option in cases involving deformity or severe instability.
He is also highly experienced in complex revision surgeries—such as converting a fused ankle to a total ankle replacement or vice versa. These technically demanding procedures require in-depth biomechanical understanding and surgical precision, both of which he brings through decades of specialization and academic involvement. His expertise spans the full range of surgical ankle treatments—from joint-preserving reconstruction to prosthesis revision.
Prof. Knupp practices at Mein Fusszentrum in Basel, a state-of-the-art medical center equipped with cutting-edge diagnostic tools and an interdisciplinary team of specialized physicians. Diagnosis, surgical planning, and follow-up care are all based on the latest scientific standards. As a professor at the University of Basel and the author of numerous publications, he plays a key role in advancing ankle surgery in the German-speaking world—especially in the fields of total ankle replacement and ankle fusion.
With over 20 years of surgical experience and several thousand successful procedures, he specializes in the treatment of degenerative conditions of the ankle joint. His focus lies in carefully balancing joint-preserving treatments and surgical interventions, tailoring each approach to the individual needs of patients with ankle osteoarthritis.
A particular emphasis is placed on total ankle replacement. Prof. Knupp performs ankle prosthesis implantation using the latest technologies, including precise 3D planning and patient-specific instrumentation. These methods enable anatomically accurate and long-lasting solutions for advanced stages of arthritis. Alternatively, he offers ankle arthrodesis (joint fusion), which remains a proven treatment option in cases involving deformity or severe instability.
He is also highly experienced in complex revision surgeries—such as converting a fused ankle to a total ankle replacement or vice versa. These technically demanding procedures require in-depth biomechanical understanding and surgical precision, both of which he brings through decades of specialization and academic involvement. His expertise spans the full range of surgical ankle treatments—from joint-preserving reconstruction to prosthesis revision.
Prof. Knupp practices at Mein Fusszentrum in Basel, a state-of-the-art medical center equipped with cutting-edge diagnostic tools and an interdisciplinary team of specialized physicians. Diagnosis, surgical planning, and follow-up care are all based on the latest scientific standards. As a professor at the University of Basel and the author of numerous publications, he plays a key role in advancing ankle surgery in the German-speaking world—especially in the fields of total ankle replacement and ankle fusion.
Facts & experience
- Foot surgeries in the last 2 years (Fußchirurgie und Sprunggelenkchirurgie)
über 870
Minimum requirement: 200
- Reconstructive foot surgeries (Fußchirurgie und Sprunggelenkchirurgie)
über 80 %
- Interventions on the rearfoot (Fußchirurgie und Sprunggelenkchirurgie)
über 600
Minimum requirement: 50
Video presentation
Expert interviews
- Expert Interview with Professor Markus Knupp, M.D. (opens in a new tab)Ankle Replacement and Osteoarthritis: Suitability, Procedure, Sports, and Therapy
- Expert Interview with Prof. Dr. med. Markus Knupp (opens in a new tab)Expert Interview with Prof. Dr. med. Markus Knupp on High-Precision Care: The Modern Ankle Prosthesis
Location
How to reach Prof. Dr. med. Markus Knupp
Mein Fusszentrum AG
Allschwilerstrasse 144055 BaselSwitzerland
Specialisation
The medical spectrum of Prof. Dr. med. Markus Knupp
Diseases
- Torn Ligament in the Ankle (opens in a new tab)
- Tendon injury (opens in a new tab)
- Sports Injuries (opens in a new tab)
- Ankle Osteoarthritis (opens in a new tab)
- Achilles tendon rupture (opens in a new tab)
- Broken bone (opens in a new tab)
- Prosthesis Infection (opens in a new tab)
- Prosthesis Loosening (opens in a new tab)
- Traumatology of the Ankle and Foot
- Cartilage Injuries
- Capsule tears
- Sprains and Capsular Tears
- Cartilage Injuries / Cartilage Reconstruction
- Tendon injuries: Achilles tendon, peroneal tendon
Treatments
- Ankle Fusion (Arthrodesis) (opens in a new tab)
- Ankle Replacement (opens in a new tab)
- Minimally Invasive Reconstructions for Ligament and Cartilage Injuries
- Primary Ankle Replacement
- Revision Ankle Prosthesis
- Conversion (Desarthrodesis) of Painful Ankylosis to Ankle Joint Prostheses
- Conversion of Painful Prostheses to Fusion / Arthrodesis
- Treatment of Advanced Osteoarthritis
Areas of Expertise
Prof. Dr. med. Markus Knupp
Specialist in ankle osteoarthritis, prosthetics, and ankle joint fusions in Basel

