Specialist · Liver Surgery
Prof. Dr. med. Dr. rer. nat. Matthias Hoffmann
Specialist for Liver Surgery, Pancreatic Surgery, Thyroid Surgery in Münster
Raphaelsklinik Münster GmbH· Loerstraße 23, 48153 Münster

Prof. Hoffmann has made a name for himself primarily as a specialist in pancreatic and liver surgery. Using state-of-the-art diagnostic and therapeutic procedures, the head physician has established the Pancreatic Cancer Center far beyond the region.
Areas of focus
- Pancreatic surgery
- Benign and malignant pancreatic diseases
- Truncus coeliacus resection
- Pancreatic cancer
- Neuroendocrine pancreatic tumors
- Liver surgery (ALPPs, extended liver resections)
- Bile duct surgery (Klatskin tumors)
- Thyroid surgery
About Prof. Dr. med. Dr. rer. nat. Matthias Hoffmann
Clemenshospital Münster is a specialized hospital in Münster with a particular focus on the treatment of oncological diseases. To this end, the Münster Alliance Against Cancer (MAgKs) was founded there as an oncology center certified by the German Cancer Society.
In the Department of General, Visceral and Vascular Surgery, all surgical procedures are performed, including extensive tumor operations affecting several organs. The department specializes in minimally invasive surgery. Particular specializations of the Department of General and Visceral Surgery are centers certified by the German Cancer Society and the German Society for General and Visceral Surgery. Patients at these centers are discussed by experts from all the specialist disciplines involved in the weekly tumor board. These include the Clemenshospital/Portal 10 Münster Colorectal Cancer Center, the Münster Pancreatic Cancer Center, the Münster Thyroid Center as a center of excellence for thyroid and parathyroid surgery, as well as the oncological focus for liver and biliary tract surgery.
The Pancreatic Cancer Center Münster treats patients with benign and malignant diseases of the pancreas. In addition to the established diagnostic procedures, all standard surgical procedures are performed. Furthermore, we have many years of experience with operations for advanced pancreatic carcinomas, including resection of the celiac trunk or the portal vein.
Due to Prof. Hoffmann's many years of experience in liver and liver transplant surgery, the surgical treatment of liver tumors is a particular focus of the department. All procedures from limited resection of liver tumors to extended liver resections and multi-stage surgical procedures (in-situ split liver resection, central "open-book" liver resection, portal vein ligation) are regularly used. These can be combined with a particularly high level of expertise in the field of interventional radiology, where the destruction of liver tumors by radiofrequency ablation, but also transarterial chemoembolisation (TACE) and interventional portal vein embolisation are used.
Endocrine surgery is a supra-regional focus of the department with over 600 thyroid operations per year. Patients with thyroid nodules, thyroid carcinomas and inflammatory thyroid diseases, as well as parathyroid diseases, are routinely operated on. The complication rates such as recurrent paresis and hypocalcaemia are well below the specified limits. Neuromonitoring of the recurrent laryngeal nerve is used in every operation. Intraoperative parathyroid hormone determination and minimally invasive video-assisted surgical techniques are standard in parathyroid surgery.
A large number of operations for colon and rectal cancer are performed at the clinic with very low complication rates in the DKG-certified Colon Cancer Center in close cooperation with specialist gastroenterological practices. Radical oncological bowel resections through to proctocolectomies with an ileo-anal pouch are performed using the laparoscopic technique as standard.
In the Department of General, Visceral and Vascular Surgery, all surgical procedures are performed, including extensive tumor operations affecting several organs. The department specializes in minimally invasive surgery. Particular specializations of the Department of General and Visceral Surgery are centers certified by the German Cancer Society and the German Society for General and Visceral Surgery. Patients at these centers are discussed by experts from all the specialist disciplines involved in the weekly tumor board. These include the Clemenshospital/Portal 10 Münster Colorectal Cancer Center, the Münster Pancreatic Cancer Center, the Münster Thyroid Center as a center of excellence for thyroid and parathyroid surgery, as well as the oncological focus for liver and biliary tract surgery.
The Pancreatic Cancer Center Münster treats patients with benign and malignant diseases of the pancreas. In addition to the established diagnostic procedures, all standard surgical procedures are performed. Furthermore, we have many years of experience with operations for advanced pancreatic carcinomas, including resection of the celiac trunk or the portal vein.
Due to Prof. Hoffmann's many years of experience in liver and liver transplant surgery, the surgical treatment of liver tumors is a particular focus of the department. All procedures from limited resection of liver tumors to extended liver resections and multi-stage surgical procedures (in-situ split liver resection, central "open-book" liver resection, portal vein ligation) are regularly used. These can be combined with a particularly high level of expertise in the field of interventional radiology, where the destruction of liver tumors by radiofrequency ablation, but also transarterial chemoembolisation (TACE) and interventional portal vein embolisation are used.
Endocrine surgery is a supra-regional focus of the department with over 600 thyroid operations per year. Patients with thyroid nodules, thyroid carcinomas and inflammatory thyroid diseases, as well as parathyroid diseases, are routinely operated on. The complication rates such as recurrent paresis and hypocalcaemia are well below the specified limits. Neuromonitoring of the recurrent laryngeal nerve is used in every operation. Intraoperative parathyroid hormone determination and minimally invasive video-assisted surgical techniques are standard in parathyroid surgery.
A large number of operations for colon and rectal cancer are performed at the clinic with very low complication rates in the DKG-certified Colon Cancer Center in close cooperation with specialist gastroenterological practices. Radical oncological bowel resections through to proctocolectomies with an ileo-anal pouch are performed using the laparoscopic technique as standard.
Special offers / services / rooms
- Modern single and double rooms with private bathroom, TV, radio, telephone, WLAN
- Comfort wards with 17 single and double rooms
- Possibility of "rooming in" for relatives
Therapeutic services
- Minimally invasive surgery
- In-situ split liver resection
- Central "open-book" liver resection
- Transanal endoscopic microsurgery (TEM)
- Truncus coeliacus resection for pancreatic corpus carcinoma
- Endoscopic submucosal dissection (ESD)
- Transarterial chemoembolisation (TACE), radiofrequency ablation (RFA)
- Psycho-oncology
- Human genetics
- Stoma and wound therapy
Diagnostic services
- Endoscopy (colonoscopy, rectoscopy, small bowel endoscopy, chromoendoscopy, narrow-band imaging)
- Endosonography incl. intervention
- ERCP
- Thin-layer CT
- Scintigraphy
- MRI/MRCP
- Intraoperative sonography and frozen section diagnostics
Insights
Insights: Raphaelsklinik Münster GmbH
Insights: Raphaelsklinik Münster GmbH – Bild 1 Insights: Raphaelsklinik Münster GmbH – Bild 2 Insights: Raphaelsklinik Münster GmbH – Bild 3
Location
How to reach Prof. Dr. med. Dr. rer. nat. Matthias Hoffmann
Raphaelsklinik Münster GmbH
General and visceral surgery
Loerstraße 2348153 MünsterGermany
Specialisation
The medical spectrum of Prof. Dr. med. Dr. rer. nat. Matthias Hoffmann
Diseases
- Hyperparathyroidism (opens in a new tab)
- Graves' disease (opens in a new tab)
- Thyroid Autonomy (opens in a new tab)
- Hyperthyroidism (opens in a new tab)
- Hypothyroidism (opens in a new tab)
- Goiter (opens in a new tab)
- Pancreatic Cancer (opens in a new tab)
- Thyroid Cancer (opens in a new tab)
- Pancreatic Diseases (opens in a new tab)
- Cirrhosis of the liver (opens in a new tab)
- Pancreatitis (opens in a new tab)
Treatments
- Endocrine Surgery (opens in a new tab)
- Pancreas Transplant (opens in a new tab)
- Liver Surgery (opens in a new tab)
- Liver Transplant (opens in a new tab)
- Parathyroid Surgery (opens in a new tab)
- Pancreatic Surgery (opens in a new tab)
- Liver Cancer Surgery (opens in a new tab)
- Minimally Invasive Liver Surgery (opens in a new tab)
- Minimally Invasive Biliary Surgery (opens in a new tab)
- Minimally Invasive Pancreatic Surgery (opens in a new tab)
- Pancreatic Cancer Surgery (opens in a new tab)
- Pancreatitis Surgery (opens in a new tab)
- Laparoscopic Pancreatic Surgery (opens in a new tab)
- Surgery for Liver Metastases (opens in a new tab)
- Cholecystectomy (opens in a new tab)
- Liver resection (opens in a new tab)
- TULC (Laparoscopic Cholecystectomy) (opens in a new tab)
- Thyroid Surgery (opens in a new tab)
Areas of Expertise
Prof. Dr. med. Dr. rer. nat. Matthias Hoffmann
Specialist for Liver Surgery, Pancreatic Surgery, Thyroid Surgery in Münster

