Arteriosclerosis: Information & arteriosclerosis doctors

Leading Medicine Guide Editors
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Leading Medicine Guide Editors

Arteriosclerosis is a chronically progressive vascular disease. Over many years, the arteries become increasingly narrowed and hardened. In the worst cases, it can lead to heart attacks, strokes or kidney failure.

Here you will find further information and selected arteriosclerosis specialists and centers.

ICD codes for this diseases: I70

Recommended specialists

Brief overview:

  • What is arteriosclerosis? A progressive vascular disease in which deposits cause the arteries to become increasingly narrow over time, which can later lead to serious complications.
  • Affected vessels: In principle, arteriosclerosis can develop in all arteries. It often develops in the branches of the cervical artery, the aorta, the femoral arteries, the coronary arteries and the cerebral arteries.
  • Causes: Various theories attempt to explain when and why arteriosclerosis occurs. Possible causes include previous damage to a vessel or increased levels of a certain blood lipid.
  • Risk factors: The development of the disease is favored by high blood pressure, an unhealthy diet, obesity, lack of exercise, smoking, stress and certain pre-existing conditions.
  • Symptoms: It can take 20 to 40 years before the first symptoms appear - usually at an advanced age. The exact symptoms depend on the vessels affected. A detailed list can be found further down in the text.
  • Diagnosis: If arteriosclerosis is suspected, a blood count is taken and various tests are carried out. These include a stress ECG, Doppler sonography and angiography.
  • Treatment: Conservative measures, such as a change to a healthier lifestyle, can slow down the progression of the disease. In severe cases, the vessels must be widened again by means of surgery.
  • Prevention: Effective prevention involves avoiding risk factors and treating pre-existing conditions.

Article overview

Definition: What is arteriosclerosis?

Arteriosclerosis is a chronically progressive vascular disease. Over the years, the arteries become increasingly narrowed and hardened.

Arteries are the blood vessels that transport blood, which in most cases is rich in oxygen, away from the heart. The blood reaches the body's organs, muscles and tissues via the arteries. The blood contains nutrients and thus ensures that these areas of the body can continue to function.

The result of these vascular changes is circulatory disorders. Over time, they reduce the blood flow and thus cause areduced oxygen supply to organs and body parts.

The best-known cause of arteriosclerosis is atherosclerosis. Among other things, blood lipids are deposited in the vessel wall (see below).

Arteriosclerosis and atherosclerosis are often used interchangeably, but this is not entirely correct. Arteriosclerosis is rather the consequence of atherosclerosis.

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The vasoconstriction and hardening of the arteries typical of atherosclerosis is caused by so-called plaques. These are deposits of

  • blood fats,
  • blood clots,
  • connective tissue and
  • calcium

in the vessel walls of the arteries. Arteriosclerosis is therefore also known colloquially as hardening of the arteries.

Older people in particular often suffer from arteriosclerosis. The disease mainly occurs in men over the age of 40 and women after the menopause.

The consequences of arteriosclerosis are the most common cause of death in western industrialized countries.

Which vessels can be affected by arteriosclerosis?

In principle, arteriosclerosis can develop in all arteries of the body . However, it occurs particularly frequently in places where the blood flow encounters physical obstacles. This is the case, for example, at vascular branches, such as

  • the cervical artery
  • the aorta and
  • the bifurcation of the femoral arteries.

In addition, arteriosclerosis often develops in the coronary

  • coronary arteries,
  • arteries supplying the brain and
  • leg arteries.

Causes and risk factors of arteriosclerosis

The exact causes that lead to the development of arteriosclerosis are not yet fully understood. However, there are various theories and explanatory models for the mechanism of the development of arteriosclerosis, including

  • "Response-to-injury" theory: primary damage to the inner vascular wall layer could favor the deposition of plaques
  • Lipid theory: certain blood fats (lipids) - the so-called LDL cholesterol - could be responsible for the development of arteriosclerosis

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Irrespective of these theories, some risk factors for the development of arteriosclerosis are known. These include

In addition, diseases such as

increase the risk of arteriosclerosis. Other risk factors are a

  • genetic predisposition,
  • older age and
  • the male sex.

Symptoms and progression of arteriosclerosis

Arteriosclerosis develops very slowly and is often asymptomatic for decades. It can take 20 to 40 years for plaques to gradually build up in the vessel walls. The increasing narrowing and hardening of the arteries then only causes the first symptoms at a late stage.

If arteriosclerosis begins in adolescence, those affected can suffer from symptoms such as circulatory disorders in the legs as early as the age of 30 to 40. In most cases, however, the first symptoms do not appear until later in life.

The exact symptoms caused by arteriosclerosis depend on the vascular sections affected.

Coronary vessels, also known as coronary arteries: These vessels supply the heart muscle. If the blood flow in the coronary arteries is reduced, those affected suffer from a feeling of tightness in the chest or left-sided chest pain(angina pectoris). Arteriosclerosis of the coronary arteries is known as coronary heart disease. In the worst case, it can trigger a heart attack .

Das Herz und die Herzkranzarterien
The coronary arteries supply the heart with oxygen © lom123 | AdobeStock

Carotid artery: memory impairment or dizziness can be a consequence. In the worst case, a stroke can occur. This can be recognized by symptoms such as neurological deficits and functional disorders of the nervous system such as paralysis or speech disorders.

Pelvic and leg arteries: Reduced blood flow to the calf and thigh muscles. This is referred to as peripheral arterial occlusive disease (PAD). Typical symptoms are severe muscle pain that occurs after walking short distances. Erectile dysfunctioncan also occur.

Renal vessels: This results in impaired kidney function - in the worst case with kidney failure - and high blood pressure.

Diagnosis of arteriosclerosis

In order to diagnose arteriosclerosis, the attending physician uses various diagnostic procedures. The first step is to take a detailed medical history and carry out a physical examination.

As part of the anamnesis, the doctor takes the patient's medical history by asking about their

  • lifestyle habits,
  • complaints and
  • previous illnesses

previous illnesses. The physical examination includes listening to the heart, the aorta or the arteries in the neck with a stethoscope and measuring blood pressure.

If these examinations confirm the suspicion of arteriosclerosis, further tests and examinations will follow. These include, for example

  • a blood test to determine cholesterol and blood sugar levels
  • an exercise ECG to determine the extent to which coronary heart disease is present
  • a Doppler sonography of the neck arteries to determine vascular constrictions in the carotid artery and assess the risk of a stroke
  • Angiography for X-ray imaging of the vessels using a contrast medium

Treatment of arteriosclerosis

Arteriosclerosis can be treated either

  • conservatively with medication and a change in lifestyle or
  • surgically as part of an operation

be treated. Which treatment approach is used in each individual case depends on the extent of the arteriosclerosis.

Conservative treatment of arteriosclerosis

Conservative, i.e. non-surgical measures are often sufficient to treat arteriosclerosis. They slow down the progression of arteriosclerosis.

Conservative treatment usually consists of a change in lifestyle and drug therapy. Lifestyle changes include in particular

  • Reduction of excess weight
  • a healthy diet
  • physical activity and exercise
  • quitting smoking

As part of the drug therapy for arteriosclerosis, for example, medication is used to inhibit blood clotting and thus prevent the formation of blood clots (thrombi). This is intended to prevent a heart attack or stroke.

In addition, medications are often used against

  • lipid metabolism disorders (so-called lipid-lowering drugs),
  • high blood pressure and
  • diabetes mellitus

are prescribed.

Surgical treatment of arteriosclerosis

If arteriosclerosis is already so advanced that a heart attack, stroke or blockage of the leg arteries is imminent, surgical treatment is necessary to widen the narrowed vessel. For example, a balloon dilatation can be performed or a bypass can be placed.

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During balloon dilatation, a balloon catheter is pushed through the bloodstream to the narrowed area and inflated. This expands the vessel and the blood can flow freely again.

During a bypass operation, the surgeon creates a bypass that guides the blood past the constricted vascular site. To do this, he uses the body's own vessel, which is usually taken from the lower leg, or a plastic vascular prosthesis.

Prevention of arteriosclerosis

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To prevent the development of arteriosclerosis, you should

  1. reduce or eliminate the known risk factors and
  2. treat the diseases that are associated with an increased risk of arteriosclerosis.

For example, overweight people should aim to lose weight. Smokers should stop or at least reduce their nicotine consumption. Diabetics should ensure that their sugar levels are correctly adjusted. Patients with high cholesterol levels should eat a low-cholesterol diet and regularly check their cholesterol levels and blood pressure.

On the other hand, a healthy, balanced and low-fat diet and regular exercise are effective measures to prevent arteriosclerosis. For example, healthy people should walk moderately for at least 150 minutes a week.

Which specialists are atherosclerosis specialists?

Specialists for arteriosclerosis are internists or cardiovascular specialists (cardiologists, vascular surgeons or cardiosurgeons). The family doctor can also carry out certain examinations and then refer the patient. They will ask the patient about their lifestyle habits and carry out a risk assessment. A blood test provides information about blood sugar and cholesterol levels. The doctor listens to abnormal blood flow noises with a stethoscope.

References

  • Ference BA et al. (2017) Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. European Heart Journal 0, 1–14. doi:10.1093/eurheartj/ehx144
  • Ludwig M (2019) Facharztwissen Angiologie: Diagnostik und Therapie arterieller, venöser und lymphatischer Erkrankungen. Springer, Heidelberg
  • Overbeck P (2017) Atherosklerose entsteht wohl anders als gedacht. Ärzte Zeitung vom 20.01.2017
  • Piepoli MF (2016) 2016 European Guidelines on cardiovascular disease prevention in clinical practice. European Heart Journal, doi:10.1093/eurheartj/ehw106
  • Schünke M et al. (2018) Prometheus. Innere Organe: LernAtlas der Anatomie. Thieme, Stuttgart
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