Spondylodiscitis: Information & spondylodiscitis specialists

Leading Medicine Guide Editors
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Leading Medicine Guide Editors

Spondylodiscitis (ICD code M46.4) is an inflammation of the vertebrae and intervertebral discs. Treatment with antibiotics is usually sufficient. Sometimes surgery is necessary for treatment.

Find more information and selected spondylodiscitis specialists here.

ICD codes for this diseases: M46.4

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Brief overview:

  • What is spondylodiscitis? An inflammatory disease of the vertebrae and intervertebral discs in the spine.
  • Causes: A bacterial infection is usually the cause, but fungi and viruses can also trigger the disease. Risk factors are diabetes, alcohol abuse, regular intake of cortisol and various pre-existing conditions.
  • Symptoms: Severe back pain that worsens with movement. This is often accompanied by the usual signs of inflammation, such as fever, night sweats, a feeling of discomfort and weakness. Later, numbness and paralysis may also occur.
  • Treatment: If left untreated, the disease can become life-threatening. After pain relief, the first priority is to identify the pathogen and treat it with appropriate medication. Surgery may be necessary under certain circumstances. Rehabilitation follows the operation.

Article overview

What is spondylodiscitis?

The human spine consists of around 33 vertebrae, which are connected to each other by the intervertebral discs. As the coccygeal vertebrae of each person are fused together to varying degrees, the total number of vertebrae varies from person to person.

The intervertebral discs act as a buffer between the individual rigid vertebrae. They ensure that the spine remains flexible and that shocks are absorbed when walking.

Many people are familiar with spinal disorders such as herniated discs or lumbago. Spondylodiscitis is less well known. The term comes from Latin and is made up of the syllables

  • "spondyl" (vertebra),
  • "disc/dis" (intervertebral disc) and
  • "itis", the suffix for an inflammatory disease.

Spondylodiscitis is therefore an inflammation of the vertebrae and intervertebral discs, i.e. both the vertebrae and intervertebral discs are affected. If only vertebral inflammation is present, it is referred to as spondylitis. In the case of pure inflammation of the intervertebral discs, this is referred to as discitis.

Anatomie der Wirbelsäule und der Bandscheiben
In spondylodiscitis, the vertebral bodies and intervertebral discs are inflamed © bilderzwerg | AdobeStock

What are the symptoms of spondylodiscitis?

Spondylodiscitis is characterized by severe back pain. The disease is accompanied by pain on exertion, which gets worse with movement. The pain in the affected area of the back manifests itself as tapping or pressure pain.

The cause of the pain is often only discovered after the patient has suffered for a long time.

In addition to back pain, some sufferers show general signs of inflammation. They suffer from fever and night sweats and feel unwell. This is usually accompanied by physical emaciation, which in turn causes

  • weakness,
  • loss of appetite and
  • weight loss

as a result.

In advanced stages, neurological deficits such as numbness or paralysis can also occur.

What are the causes of spondylodiscitis?

Spondylodiscitis is usually caused by a bacterial infection. In most cases, the bacterium Staphylococcus aureus is the responsible pathogen. However, fungi and viruses can also be the cause of spondylodiscitis.

A basic distinction is made between specific spondylodiscitis and non-specific spondylodiscitis.

Specific spondylodiscitis (also known as skeletal tuberculosis) is caused by tubercle bacilli. It occurs less acutely than non-specific spondylodiscitis and has a more gradual course. The infection occurs via the bloodstream. However, this disease has now become rare in our country.

In addition to the aforementioned Bakerium, all other pyogenic pathogens can also cause non-specific spondylodiscitis. The disease is accompanied by acute pain. The cause of the inflammation can be open bone fractures. Bacteria can enter the body through the wound and thus into the bone.

However, the pathogens can also reach the spine via the bloodstream through inflammation sites anywhere in the body.

Risk factors for the development of spondylodiscitis are

  • Diabetes,
  • excessive alcohol consumption,
  • regular cortisol intake and
  • many other diseases.

What is the treatment for spondylodiscitis?

Early diagnosis can significantly improve and shorten the course of spondylodiscitis. If the disease remains untreated, this can result in severe symptoms and even a life-threatening course.

However, treatment with antibiotics is often sufficient. The body can then bring the inflammation under control. Nevertheless, consequential damage often remains: in many people, the intervertebral discs remain damaged and the vertebrae stiffen as the disease progresses.

Treatment of spondylodiscitis initially focuses on containing the pain.

Before the actual treatment, the germ or pathogen spectrum must be identified. This requires a biopsy (tissue sample) or surgery. The biopsy is CT-supported, even if no operation is performed. Whether surgery is necessary for the treatment of spondylodiscitis depends on

  • the extent of the damage,
  • the pain and
  • the neurological deficits

and the neurological deficits.

If surgery is performed, the surgeon removes the area of inflammation and stabilizes it. This allows the patient to be mobilized quickly and improves their pain.

Without surgery, the patient is initially recommended bed rest until the pain is under control. Drug therapy with antibiotics is usually carried out for 6 to a maximum of 12 weeks. This eliminates the focus of inflammation and prevents it from spreading to other regions of the body.

If the inflammation is not bacterial, but caused by fungi or other pathogens, antifungal or antiparasitic therapy is required.

In addition to drug therapy, the affected vertebral region must be immobilized. Bed rest and a plaster cast have proven effective for this.

After around 10 weeks, exercise therapy is carefully started in order to stabilize the spine.

References

  • Sobottke R at al., Aktuelle Diagnostik und Therapie der Spondylodiszitis. Dtsch Arztebl 2008; 105(10):181–187; DOI: 10.3238/arztebl.2008.0181
  • Michiels I & Jäger M. Spondylodiszitis – Aktuelle Strategien zur Diagnose und Therapie. Der Orthopäde 2017; 9: https://doi.org/10.1007/s00132-017-3436-0
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