Prof. Dr. med. Robert Rosenberg FACS, EMBA

Liebl F, Demir IE, Mayer K, D’Haese JG, Becker K, Langer R, Bergmann F, Schuster T, Rosenberg R, Novotny AR, Feith M, Reim D, Friess H, Ceyhan GO
Comprehensive characterization of neural invasion in gastrointestinal
cancers – a clinicopathological study of 2050 cases
Ann Surg 2014, accepted

Croner RS, Geppert C, Bader FG, Nitsche U, Rosenberg R, Zettl A, Matias-Guiu X, Tarragona J, Güller U, Stürzl M, Zuber M
Upstaging of patients with lymph node negative colon carcinomas by One-Step Nucleic Acid Amplification (OSNA): Results of the Prospective, European, Multicenter Study
Br J Cancer 2014, Apr 10 (Epub ahead of print)

Bundschuh RA, Dinges J, Neumann L, Seyfried M, Papp L, Rosenberg R, Becker K, Astner S, Hermann K, Ziegler S, Schwaiger M, Essler M
Textural parameters of tumor heterogeneity in FDG-PET/CT for therapy response assessment and prognosis in patients with locally advanced colorectal cancer
J Nucl Med 2014, Apr 21 (Epub ahead of print)

Drecoll E, Nitsche U, Bauer K, Berezowska S, Slotta-Huspenina J, Rosenberg R, Langer R
Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma
Int J Colorectal Dis 2014 Apr 15 (Epub ahead of print)

Roepman P, Schlicker A, Tabernero J, Tian S, Moreno V, Snel M, Majewski I, Orphanides G, Rosenberg R, Nitsche U, Capella G, Salazar R, Wessels L, Bernards R, Simon I
Colorectal cancer intrinsic subtypes are associated with prognosis and chemotherapy response and linked to deficient mismatch repair and epithelial to mesenchymal transition.
Int J Cancer 2014, 134: 552-62

Nitsche U, Zimmermann A, Späth C, Müller T, Maak M, Schuster T, Slotta-Huspenina J, Käser S, Michalski CW, Janssen KP, Friess H, Rosenberg R, Bader FG
Mucinous and Signet-ring cell Colorectal Cancers differ from classical Adenocarcinoma in Tumor Biology and Prognosis
Ann Surg 2013, 258: 775-82

Rosenberg R
Snapshot of the month and front cover image: De Garengeot's Hernia
Br J Surg 2013, 100: 767

Maak M, Simon I, Nitsche U, Roepman P, Snel M, Glas A, Schuster T, Keller G, Zeestraten E, Goossens I, Janssen KP, Friess H, Rosenberg R
Independent validation of a prognostic genomic signature (ColoPrint) for stage II colon cancer patients
Ann Surg 2013, 257: 1053-1085

Nitsche U, Rosenberg R, Balmert A, Schuster T, Slotta-Huspenina J, Herrmann P, Bader FG, Friess H, Schlag PM, Stein U, Janssen KP
Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer
Ann Surg 2012, 256: 763-771

Ebert PA, Tänzer M, Balluff B, Burgermeister E, Kretzschmar A, Hughes D, Tetzner R, Lofton-Day C, Rosenberg R, Reinacher-Schick A, Schulmann K, Tannapfel A, Hofheinz R, Röcken C, Keller G, Langer R, Specht K, Porschen R, Stöhlmacher J, Schuster T, Ströbel P, Schmid RM
Epigenetic regulation of transcription factor AP-2 epsilon (TFAP2e) mediates chemoresistance in colorectal cancer via dickkopf homolog 4
N Engl J Med 2012; 366: 44-53

Zeestraten ECM, Maak M, Shibayama M, Schuster T, Nitsche U, Matsushima T, Nakayama S, Gohda K, Friess H, van de Velde CJH, Ishihara H, Rosenberg R, Kuppen PJK, Janssen KP
Specific activity of cyclin dependent kinase 1 predicts tumor recurrence in stage II colon cancer
Br J Cancer 2012; 106: 133-40


Nitsche U, Maak M, Schuster T, Künzli B, Langer R, Slotta-Huspenina J, Janssen KP, Friess H, Rosenberg R
Prediction of prognosis is not improved by the 7th and latest edition of the TNM classification for colorectal cancer in a single-center collective
Ann Surg. 2011; 254: 793-801

Ceyhan GO, Liebl F, Maak M, Schuster T, Becker K, Langer R, Demir IE, Hartel M, Friess H, Rosenberg R
The severity of neural invasion is a crucial prognostic factor in rectal cancer independent of neoadjuvant radiochemotherapy
Ann Surg 2010; 252: 797–804

Rosenberg R, Engel J, Bruns C, Heitland W, Hermes N, Jauch KW, Kopp R, Pütterich E, Ruppert R, Schuster T, Friess H, Hölzel D
The prognostic value of lymph node ratio in a population-based collective of colorectal cancer patients
Ann Surg; 2010; 251: 1070-8

Rosenberg R, Friess H
Re: Should Total Number of Lymph Nodes be Used as a Quality of Care Measure for Stage III Colon Cancer? Wang J et al. Ann Surg 2009; 249: 559-563
Ann Surg 2010; 251: 183; author reply 184-5

Rosenberg R, Friederichs J, Schuster T, Gertler R, Maak M, Becker K, Grebner A, Ulm K, Höfler H, Nekarda H, Siewert JR
Prognosis of patients with colorectal cancer is associated with lymph node ratio. A single-center analysis of 3026 patients over a 25-year time period
Ann Surg 2008; 248: 968-978

Hüser N, Michalski CW, Erkan M, Schuster T, Rosenberg R, Kleef J, Friess H
Systemic review and met-analysis of the role of defunctioning stoma in low rectal cancer surgery: Is it needed?
Ann Surg 2008, 248: 52-60

Gertler R, Doll D, Maak M, Feith M, Rosenberg R
Telomere Length and Telomerase Subunits as diagnostic and prognostic biomarkers in Barrett’s Carcinoma
Cancer 2008; 112: 2173-2180
Impact 5,2
Rimkus C, Friederichs J, Boulesteix AL, Theisen J, Mages J, Rosenberg R, Janssen KP, Siewert JR
Microarray based prediction of tumor response to neoadjuvant chemoradiotherapy of patients with locally advanced rectal cancer
Clin Gastroenterology Hepatology 2008, 6: 53-61

Bembenek A, Rosenberg R, Wagler E, Gretschel S, Sendler A, Siewert JR, Nährig J, Witzigmann H, Hauss J, Knorr C, Dimmler A, Gröne J, Buhr HJ, Haier J, Herbst H, Tepel J, Siphos B, Kleespies A, Koenigsrainer A, Stoecklein NH, Horstmann O, Grützmann R, Imdahl A, Svoboda D, Wittekind C, Wernecke KD, Schlag PM
Sentinel Lymph Node Biopsy in Colon Cancer: a Prospective German Multicenter Trial
Ann Surg 2007, 245: 858-863

Rosenberg R, Nekarda H, Bauer P, Friederichs J, Rimkus C, Gertler R, Brunold D, Schenck U, Höfler H, Siewert JR
Prognostic value of immunocytochemically detected free peritoneal tumor cells in 346 patients with curatively resected gastric carcinoma
Br J Surg 2006, 93: 325-331

Rimkus C, Martini M, Friederichs J, Rosenberg R, Doll D, Siewert JR, Holzmann B, Janssen KP
Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer
Br J Cancer 2006, 95: 1419-1423

Gertler R, Rosenberg R, Stricker D, Friederichs J, Hoos A, Werner M, Ulm K, Nekarda H, Siewert JR
Telomere Length and hTERT Expression as Markers for Progression and Prognosis of Colorectal Carcinoma
J Clin Oncol 2004, 22: 1807-1814

Rosenberg R, Hoos A, Mueller J, Baier P, Stricker D, Werner M, Nekarda H, Siewert JR
Prognostic Significance of Cytokeratin-20 RT-PCR in Lymph Nodes of Node Negative (pN0) Colorectal Cancer Patients
J Clin Oncol 2002, 20: 1049-1055

Gertler R, Rosenberg R, Stricker D, Werner M, Lassmann S, Ulm K, Nekarda H, Siewert JR
Prognostic potential of the telomerase subunit human telomerase reverse transcriptase in tumor tissue and nontumorous mucosa from patients with colorectal carcinoma
Cancer 2002, 95: 2103-2111

Thorban S, Rosenberg R, Busch R, Roder J
Epithelial cells in bone marrow of esophageal cancer patients: a significant prognostic factor in multivariate analysis
Br. J. Cancer 2000, 83: 35-39

Rosenberg R, Hoos A, Mueller J, Nekarda H
Cytokeratin-20 and Carcinoembryonic antigen mRNA detection by RT-PCR in regional lymph nodes: differing prognostic impact in patients with pN0 colorectal carcinoma
Br. J. Cancer 2000, 83: 1323-1329

• Diagnostische Laparoskopie
• Diagnostische Thorakoskopie
• Interventionelle Gefässuntersuchungen
• Sonographie
• Magnetresonanztomographie
• Computertomographie
• Positronenemissionstomographie-CT
• Diagnostische Ösophagusröntgenuntersuchungen
• Rektoskopie
• Analmanometrie
• Endosonographie
• Defäkographie

Kooperation mit Spezialdisziplinen:

Gleichermassen profitieren die Patienten von vielfältigen Kooperationsmöglichkeiten am KSBL. So besteht eine enge interdisziplinäre Zusammenarbeit mit den Spezialisten für:

• Orthopädie
• Urologie
• Gynäkologie
• Plastische Chirurgie
• Schmerztherapie/Anästhesie
• Physio- und Ergotherapie